麻醉深度监测设备检测方法研究

解涛瑞; 马雪然; 陈达; 梁俊辉; 定翔

doi:10.12338/j.issn.2096-9015.2024.0016

麻醉深度监测设备检测方法研究

doi: 10.12338/j.issn.2096-9015.2024.0016

解涛瑞^{1, 2,},
马雪然¹,
陈达²,
梁俊辉²,
定翔^1, ,

1.
中国计量科学研究院，北京 100029
2.
中国计量大学，杭州 310018

基金项目: 国家重点研发计划项目（2022YFF0606102）。

详细信息

作者简介:
解涛瑞（1999-），中国计量科学研究院在读研究生，研究方向：医学计量，邮箱：Tory.R.Xie@outlook.com

通讯作者:
定翔（1984-），中国计量科学研究院副研究员，研究方向：医学计量，邮箱：dingxiang@nim.ac.cn

中图分类号: TB99
计量
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- 被引次数: 0
出版历程
- 收稿日期: 2024-01-16
- 录用日期: 2024-02-22
- 修回日期: 2024-05-15
- 网络出版日期: 2024-05-30

Research on Calibration Methods for Anesthetic Depth Monitoring Devices

XIE Taorui^{1, 2
,},
MA Xueran¹,
CHEN Da²,
LIANG Junhui²,
DING Xiang^{1
, ,}

1.
National Insitute of Metrology, Beijing 100029, China
2.
China Jiliang University, Hangzhou 310018, China

摘要

摘要: 针对麻醉深度监测设备计量检测和性能评价方法缺失的问题，提出采用临床采集的真实脑电信号评价麻醉深度指数测量结果的方法。利用自制麻醉深度监测设备检测系统，将青年和老年患者的麻醉状态脑电信号输入BIS指数、CSI指数、Ai指数等三种麻醉深度监测设备，对测量结果的一致性和重复性进行了计算和评估，分析了指数与脑电信号频谱的相关性。三种指数在反映麻醉状态变化的整体趋势上有较好的一致性，但在麻醉过渡状态和老年患者样本的情况下表现出显著差异。结果表明该方法可用于三种麻醉深度监测设备的检测，对开展麻醉深度监测设备计量质控具有一定的指导意义。
- 计量学 /
- 麻醉深度指数 /
- 脑电信号 /
- 麻醉深度监测设备
Abstract: To address the lack of calibration and performance evaluation methods for anesthetic depth monitoring devices, a new approach is proposed that utilizes real clinical electroencephalogram (EEG) signals to assess the measurement results of anesthetic depth indices. Using a custom-built anesthetic depth monitoring device testing system, EEG signals from young and elderly patients under anesthesia were input into three anesthetic depth monitoring devices, namely BIS index, CSI index, and Ai index. The consistency and repeatability of the measurement results were calculated and evaluated, and the correlation between the indices and the EEG signal spectrum was analyzed. The three indices showed good overall consistency in reflecting the changes in anesthetic state, but significant differences were observed during the anesthetic transition state and in samples from elderly patients. The results indicate that this method can be used for testing the three anesthetic depth monitoring devices and provides guidance for conducting metrological quality control of these devices.
- metrology /
- anesthetic depth index /
- EEG signal /
- anesthetic depth monitoring devices

HTML全文

图 1 不同麻醉状态下脑电波图

Figure 1. EEG waveforms under different anesthetic states

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图 2 麻醉术中患者脑电频谱的变化

Figure 2. Changes in patients’ EEG spectrum during anesthesia

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图 3 浅麻状态下年轻患者与老年患者的脑电信号

Figure 3. EEG signals of young and elderly patients under light anesthesia

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图 4 麻醉深度监测设备与信号发生装置连接方式

Figure 4. Connection between the anesthetic depth monitoring device and the signal generating device

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图 5 青年患者麻醉深度指数变化

Figure 5. Changes in the anesthetic depth index of a young patient

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图 6 老年患者麻醉深度指数变化

Figure 6. Changes in the anesthetic depth index of an elderly patient

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图 7 三种麻醉深度指数连续测量的示值波动线图

Figure 7. Error line graph for continuous measurements of three anesthetic depth indices

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图 8 年轻患者(左)与老年患者(右)麻醉过程中脑电信号频谱

Figure 8. EEG signal spectrum during anesthesia in young patients (left) and elderly patients (right)

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