内窥式光学相干多普勒流速检测方法的研究

    Study of Flow Velocity Detection by Endoscopic Doppler Optical Coherence Tomography

    • 摘要: 在扫频光学相干层析成像(SS-OCT)和相位分辨多普勒算法的基础上搭建了一套内窥光学相干多普勒系统,采用了基于GRIN透镜和MEMS微镜的内窥探头,实现了对样品流速信息的测量。经性能测试,得到本系统的轴向分辨率为6.88 μm,横向分辨率为15.79 μm,成像深度约为3.4 mm;系统在输出1000×1024尺寸的二维图像时,可以实现50 frame/s的成像速度。利用琼脂和毛细玻璃管进行流速测量的模拟实验,经验证搭建的系统能够得到被测截面的流速分布,测得的分布情况基本上与理论一致。设置注射泵在不同流速时分别进行实验,测得的流速平均值与设定值在误差范围内基本符合。结果表明,设计的基于MEMS微镜的内窥光学相干多普勒系统能够良好的满足层析成像和流速检测的要求。

       

      Abstract: An endoscopic Doppler OCT system based on swept-source optical coherence tomography (SS-OCT) and phase-resolved Doppler algorithms was constructed in the study, and an endoscopic probe based on GRIN lenses and MEMS micromirrors was used to realize the measurement of flow rate information. After performance testing, the axial resolution of the system was obtained to be 6.88 μm, the lateral resolution was 15.79 μm, and the imaging depth was about 3.4 mm; the system could realize an imaging speed of 50 frames/s when outputting a 2D image of 1000×1024 size. Simulation experiments of flow rate measurement using agar and capillary glass tubes were carried out, and it was verified that the system constructed in this paper could obtain the flow rate distribution of the cross-section under test, and the measured distribution was basically consistent with the theory. The syringe pump was set to perform experiments at different flow rates, and the measured average flow rate values were basically consistent with the set values within the error range. The results show that the endoscopic Doppler OCT system based on MEMS micromirror designed in this paper can well meet the needs of laminar imaging and flow velocity detection.

       

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