Abstract: In June 2021, the Consultative Committee for Amount of Substance: Metrology in Chemistry and Biology (CCQM) released its development strategy for 2021-2030. This document outlines the vision, primary objectives, and strategic goals for the next decade, adhering to its mission of enhancing the global comparability of chemical and biological measurement standards and capabilities. This article organizes and summarizes the main content of the strategic plan, offering insights into the future developmental trends and key areas in the ‘amount of substance’ field. Understanding the CCQM development strategy helps in positioning China’s metrological strategic choices in the ‘amount of substance’, building strategic bilateral and multilateral relationships, innovating development models, and making a leap from aligning with international standards to leading development in this domain.