Study of IAEA TRS-398 and Its Application in Clinical Dosimetry
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摘要: 为降低临床放射治疗剂量测量的不确定度,讨论并对比了直接测量处方剂量:水吸收剂量的方法TRS-398报告应用于临床的优势。通过介绍在不同种类射线下直接测量水吸收剂量的条件与方法,汇总目前基于TRS-398报告测量方法的部分实验数据,结果表明:TRS-398报告方法测量剂量与277报告方法测量剂量在允许测量不确定度以内一致,表明398报告方法测量结果可靠,且满足临床剂量输出不确定度5%(k=1)以内的要求。这一结果为更新临床放射治疗剂量输出测量的方法提供理论依据。Abstract: The advantages of the direct measurement method for absorbed dose to water in Report TRS-398 were studied. This is a promising method for determining prescription dose in clinical applications and reducing the uncertainty of clinical radiotherapy dosimetry. By introducing the conditions and methods for directly measuring the absorbed dose to water under different kinds of radiation, part of the experimental data based on TRS-398 report measurement method is summarized. The results show that the repeatability of the direct measurement method is less than 0.5% and the uncertainty of dose measurement is less than 2%. The direct measurement method for absorbed dose to water meets the uncertainty requirement of clinical dose outputs, i.e. less than 5% (k=1). These results provide a theoretical basis for updating the method of dose output measurement in clinical radiotherapy.
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