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GBW(E)100674乙腈中展青霉素溶液标准物质的研制

李先江 国振 赵光亮 李秀琴 张庆合 李红梅

李先江,国振,赵光亮,等. GBW(E)100674乙腈中展青霉素溶液标准物质的研制[J]. 计量科学与技术,2021, 65(6): 34-38, 24 doi: 10.12338/j.issn.2096-9015.2020.9047
引用本文: 李先江,国振,赵光亮,等. GBW(E)100674乙腈中展青霉素溶液标准物质的研制[J]. 计量科学与技术,2021, 65(6): 34-38, 24 doi: 10.12338/j.issn.2096-9015.2020.9047
LI Xianjiang, GUO Zhen, ZHAO Guangliang, LI Xiuqin, ZHANG Qinghe, LI Hongmei. Development of Certified Reference Materials of Patulin in Acetonitrile GBW(E)100674[J]. Metrology Science and Technology, 2021, 65(6): 34-38, 24. doi: 10.12338/j.issn.2096-9015.2020.9047
Citation: LI Xianjiang, GUO Zhen, ZHAO Guangliang, LI Xiuqin, ZHANG Qinghe, LI Hongmei. Development of Certified Reference Materials of Patulin in Acetonitrile GBW(E)100674[J]. Metrology Science and Technology, 2021, 65(6): 34-38, 24. doi: 10.12338/j.issn.2096-9015.2020.9047

GBW(E)100674乙腈中展青霉素溶液标准物质的研制

doi: 10.12338/j.issn.2096-9015.2020.9047
基金项目: 国家重点研发计划(2016YFF0201106)
详细信息
    作者简介:

    李先江(1988-),中国计量科学研究院副研究员,研究方向:食品安全,邮箱:lixianjaing@nim.ac.cn

Development of Certified Reference Materials of Patulin in Acetonitrile GBW(E)100674

  • 摘要: 本课题研制了乙腈中展青霉素的溶液标准物质1种, 并已成功申报为国家二级标准物质(GBW(E)100674)。该溶液标准物质以展青霉素纯度国家二级标准物质(GBW(E)100673)为原料,采用重量容量法配制。依据JJF 1343-2012《标准物质定值的通用原则及统计学原理》的要求, 本研究采用液相色谱法对乙腈中展青霉素溶液标准物质进行均匀性、短期稳定性和长期稳定性的评价。定值不确定度包含原料纯度、溶液配制、均匀性、短期稳定性和长期稳定性五个方面引入的不确定度。最终,该溶液标准物质GBW(E)100674的定值结果为100 µg/mL,不确定度为2%。本研究研制展青霉素溶液标准物质的量值具有溯源性和准确性,可以支持国家食品安全检测的需要。
  • 图  1  展青霉素溶液标准物质和溶剂空白的色谱图

    Figure  1.  Chromatogram of the patulin CRM and blank

    图  2  展青霉素溶液标准物质均匀性检验结果(100 μg/ mL)

    Figure  2.  Homogeneity test result of the patulin CRM (100 μg/mL)

    图  3  展青霉素标准物质的稳定性变化趋势

    Figure  3.  Short-term stability of the patulin CRM at 40 ℃

    图  4  展青霉素标准物质的稳定性变化趋势

    Figure  4.  Short-term stability of the patulin CRM at 4 ℃

    图  5  长期稳定性监测结果

    Figure  5.  Long-term stability of the patulin CRM

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出版历程
  • 网络出版日期:  2021-06-09
  • 刊出日期:  2021-07-08

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