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不同定量方法在婴儿配方奶粉中维生素B12测量中的不确定度评估

王许欣 李晓敏 张庆合

王许欣,李晓敏,张庆合. 不同定量方法在婴儿配方奶粉中维生素B12测量中的不确定度评估[J]. 计量科学与技术,2022, 66(9): 23-27, 46 doi: 10.12338/j.issn.2096-9015.2022.0089
引用本文: 王许欣,李晓敏,张庆合. 不同定量方法在婴儿配方奶粉中维生素B12测量中的不确定度评估[J]. 计量科学与技术,2022, 66(9): 23-27, 46 doi: 10.12338/j.issn.2096-9015.2022.0089
WANG Xuxin, LI Xiaomin, ZHANG Qinghe. Uncertainty Evaluation of Different Quantitative Calibration Methods for the Determination of Vitamin B12 in Infant Formula[J]. Metrology Science and Technology, 2022, 66(9): 23-27, 46. doi: 10.12338/j.issn.2096-9015.2022.0089
Citation: WANG Xuxin, LI Xiaomin, ZHANG Qinghe. Uncertainty Evaluation of Different Quantitative Calibration Methods for the Determination of Vitamin B12 in Infant Formula[J]. Metrology Science and Technology, 2022, 66(9): 23-27, 46. doi: 10.12338/j.issn.2096-9015.2022.0089

不同定量方法在婴儿配方奶粉中维生素B12测量中的不确定度评估

doi: 10.12338/j.issn.2096-9015.2022.0089
基金项目: 国家重点研发计划课题(2019YFC1604803)。
详细信息
    作者简介:

    王许欣(1997-),中国计量科学研究院在读硕士研究生,研究方向:食品中维生素计量技术研究,邮箱:wangxuxin0101@163.com

    通讯作者:

    李晓敏(1981-),中国计量科学研究院副研究员,研究方向:食品质量安全与化学计量,邮箱:lixm@nim.ac.cn

Uncertainty Evaluation of Different Quantitative Calibration Methods for the Determination of Vitamin B12 in Infant Formula

  • 摘要: 本文以婴儿配方奶粉中的维生素B12测量为例,开展了标准加入法、标准加入同位素稀释质谱法、单点同位素稀释质谱法和校准曲线同位素稀释质谱法四种定量方法的不确定度评估。基于ISO-GUM指南等不确定度评估方法对四种定量方法进行不确定度量化评估,发现方法重复性和曲线拟合引入的不确定度为主要不确定度来源,且标准加入法评估得到的不确定度明显大于同位素内标法评估得到的不确定度。通过不同定量方法的比较研究,可以更有效地选择定量方式,提高测量精度。
  • 图  1  不同定量方法不确定度及分量的比例

    Figure  1.  Uncertainty values of different quantitative methods with contribution from associate components

    表  1  不同定量方法相关分量相对标准不确定度

    Table  1.   Relative standard uncertainty values of each components of the quantitative methods

    不确定度来源SASA-IDMSSP-IDMSSCC-IDMS
    A类不确定度重复性uref,rep3.3%1.1%1.6%1.3%
    B类不确定度标准物质纯度uref,p0.4%0.4%0.4%0.4%
    溶液制备与称量uref,w0.1%0.1%0.1%0.2%
    校准曲线urel,cal6.3%2.5%/2.6%
    合成不确定度7.2%2.8%1.7%3.0%
    扩展不确定度U(k=2)14.4%5.6%3.4%6.0%
    下载: 导出CSV
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出版历程
  • 网络出版日期:  2022-09-06
  • 刊出日期:  2022-09-30

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