留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

基于Lambert-Beer定律修正血氧饱和度R值曲线

马俊 刘刚 李超 闻倩宇

马俊,刘刚,李超,等. 基于Lambert-Beer定律修正血氧饱和度R值曲线[J]. 计量科学与技术,2023, 67(1): 23-28 doi: 10.12338/j.issn.2096-9015.2022.0252
引用本文: 马俊,刘刚,李超,等. 基于Lambert-Beer定律修正血氧饱和度R值曲线[J]. 计量科学与技术,2023, 67(1): 23-28 doi: 10.12338/j.issn.2096-9015.2022.0252
MA Jun, LIU Gang, LI Chao, WEN Qianyu. Correction and Calibration of R Value Curve for Blood Oxygen Saturation Measurement Model Based on Lambert-Beer Law[J]. Metrology Science and Technology, 2023, 67(1): 23-28. doi: 10.12338/j.issn.2096-9015.2022.0252
Citation: MA Jun, LIU Gang, LI Chao, WEN Qianyu. Correction and Calibration of R Value Curve for Blood Oxygen Saturation Measurement Model Based on Lambert-Beer Law[J]. Metrology Science and Technology, 2023, 67(1): 23-28. doi: 10.12338/j.issn.2096-9015.2022.0252

基于Lambert-Beer定律修正血氧饱和度R值曲线

doi: 10.12338/j.issn.2096-9015.2022.0252
详细信息
    作者简介:

    马俊 (1987-),北京市海淀区计量检测所工程师,研究方向:流量计量、医学计量等,邮箱:305171336@qq.com

Correction and Calibration of R Value Curve for Blood Oxygen Saturation Measurement Model Based on Lambert-Beer Law

  • 摘要: 针对血氧模拟仪现有的R值曲线无法满足种类繁多的血氧仪计量检定需求,为解决血氧仪与模拟仪不兼容问题,提出一种基于Lambert-Beer定律的血氧饱和度测量模型的修正方法。在现有的检定装置上添加滤光介质,以实现在原有的测量模型上加一个修正值,从而对R值曲线进行修正。实验表明,通过添加滤光介质修正R值曲线,选择不同R值曲线检测血氧仪时均显示出正常的测量值,且示值重复性较小,符合国家计量检定规程要求,有效解决了血氧模拟仪与血氧仪之间的不兼容问题。
  • 图  1  透射式血氧仪测量原理示意图

    Figure  1.  Schematic diagram of transmission-type oximeter measurement principle

    图  2  光电容积脉搏波形成模型图

    Figure  2.  Schematic diagram of photoplethysmography (PPG) pulse wave formation model

    图  3  HbO2与Hb摩尔消光系数图

    Figure  3.  Molar absorption coefficient diagram of HbO2 and Hb

    图  4  模拟手指与监护仪指夹连接图

    Figure  4.  Schematic diagram of connection between simulated finger and monitor finger clip

    图  5  复印纸光谱曲线图

    Figure  5.  Spectrogram of photocopy paper

    表  1  不同R值曲线的血氧饱和度测量值

    Table  1.   Oxygen saturation measurements with different R value curves of the monitor

    标准值
    (%)
    Nellcor
    (%)
    BCI
    (%)
    Datascope
    (%)
    Datex
    (%)
    Masimo
    (%)
    1008999///
    958999///
    908999///
    858999///
    808999///
    708999///
    注:“/”表示未显示任何数值。
    下载: 导出CSV

    表  2  加滤光介质后监护仪血氧模块测量值

    Table  2.   Measurement value of blood oxygen module of monitor after adding optical filter medium

    标准值
    (%)
    Nellcor
    (%)
    BCI
    (%)
    Datascope
    (%)
    Datex
    (%)
    Masimo
    (%)
    100100100100100100
    959595949595
    909091899192
    858486838485
    807981787880
    707271656769
    下载: 导出CSV

    表  3  加滤光介质后监护仪血氧模块示值重复性

    Table  3.   Indication repeatability of blood oxygen module of monitor after adding optical filter medium

    标准值(%)R值曲线被检监护仪测量值(%)示值重复性(%)
    100Nellcor1001001001001001000.0
    909090919091910.5
    707172717172710.5
    100BCI1001001001001001000.0
    909191909091910.5
    707271717272720.5
    100Datascope1001001001001001000.0
    908988888989880.5
    706566666564650.8
    100Datex1001001001001001000.0
    909192929192910.5
    706768676768680.5
    100Masimo1001001001001001000.0
    909292939393930.5
    706969706969710.8
    下载: 导出CSV
  • [1] 徐楚天, 徐向天, 张玉华, 等. 动脉氧分压与脉搏血氧饱和度相关性研究及临床应用[J]. 中国医学装备, 2019, 16(3): 83-87. doi: 10.3969/J.ISSN.1672-8270.2019.03.023
    [2] 严新忠, 杨静, 郭略. 人体血氧饱和度监测方法的研究. 医疗装备, 2005, 18(12): 1-3.
    [3] Jung S J, Lee Y D, Seo Y S, et al. Design of a low-power consumption wearable reflectance pulse oximetry for ubiquitous healthcare system[C]//International Conference on Control. IEEE, 2008: 526-529.
    [4] Frehill P, Chambers D, Rotariu C. Using Zigbee to Integrate Medical Devices[C]//2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2007: 6717-6720.
    [5] Tavakoli M, Turicchia L, Sarpeshkar R. An ultra-low-power pulse oximeter implemented with an energy-efficient transimpedance amplifier[J]. IEEE Transactions on Biomedical Circuits & Systems, 2010, 4(1): 27-38.
    [6] Aoyagi T. Pulse oximetry and its simulation[J]. IEEE Tokyo Section Denshi Tokyo, 1990, 29: 184-187.
    [7] Aoyagi T, Fuse M, Kobayashi N, et al. Optics of pulse photometer No. 2[J]. Jpn J Med Elec Biol Eng, 2002, 39: 55.
    [8] Robert Finnerty. How to design a better pulse oximeter [J/OL]. ANALOG DEVICES. 2021: 1-5[2022-12-18].https://www.analog.com/cn/technical-articles/how-to-design-a-better-pulse-oximeter.html.
    [9] Aoyagi T. Pulse oximetry: its invention, theory, and future[J]. Journal of Anesthesia, 2003, 17: 259-266. doi: 10.1007/s00540-003-0192-6
    [10] 曹云皓, 杨喜业, 刘春晨, 等. 有机/聚合物光探测器在医疗健康领域中的应用[J]. 高分子学报, 2022, 53(4): 307-330. doi: 10.11777/j.issn1000-3304.2021.21391
    [11] Kock J P D, Tarassenko L. Pulse oximetry: theoretical and experimental models[J]. Medical & Biological Engineering & Computing, 1993, 31(3): 291-300.
    [12] 陈意, 李凯扬. 三波长血氧饱和度定标曲线的研究[J]. 北京生物医学工程, 2021, 40(5): 499-504. doi: 10.3969/j.issn.1002-3208.2021.05.009
    [13] 郭萍, 孙卫新, 金捷, 等. 脉搏血氧仪定标曲线的研究[J]. 西安医科大学学报(中文版), 2000(2): 169-171.
    [14] 张磊. 血氧饱和度曲线的选取及性能测试过程中的重要影响[J]. 计量与测试技术, 2019, 46(10): 48-49,53. doi: 10.15988/j.cnki.1004-6941.2019.10.017
    [15] M Vegfors, L G Lindberg, P Å Öberg, et al. Accuracy of pulse oximetry at various haematocrits and during haemolysis in anin vitro model[J]. Medical and Biological Engineering and Computing, 1993, 31(1): 135-141.
    [16] 王耀弘, 周中木, 张雯. 一种脉搏血氧仪校准装置的设计[J]. 计量与测试技术, 2020, 47(11): 39-41. doi: 10.15988/j.cnki.1004-6941.2020.11.012
    [17] 蒲莉娜, 潘颂欣, 林宛华, 等. 脉搏血氧饱和度测量精度的影响因素分析[J]. 中国医疗器械信息, 2010, 16(6): 11-15,46. doi: 10.3969/j.issn.1006-6586.2010.06.004
    [18] 刘文丽, 胡志雄, 杨世金, 等. 《JJG 1163-2019多参数监护仪检定规程》编制说明[J]. 中国医疗设备, 2021, 36(8): 148-151,164. doi: 10.3969/j.issn.1674-1633.2021.08.036
    [19] 刘文丽, 胡志雄, 贾建革, 等. 多参数监护仪检定规程: JJG 1163-2019[S]. 北京: 国家市场监督管理总局, 2019.
  • 加载中
图(5) / 表(3)
计量
  • 文章访问数:  254
  • HTML全文浏览量:  97
  • PDF下载量:  47
  • 被引次数: 0
出版历程
  • 网络出版日期:  2023-01-18
  • 刊出日期:  2023-01-18

目录

    /

    返回文章
    返回