Mass Spectrometry Matrix Effect Study for the Trace Analysis of Chloramphenicol Residues in Honey

TIAN Tian; LIU Shuyu; ZHANG Yan; ZHOU Xia; JIAO Hui; LI Xiuqin

doi:10.12338/j.issn.2096-9015.2020.9037

Volume 65 Issue 5

Jun. 2021

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Article Navigation > Metrology Science and Technology > 2021 > 65(5): 77-82, 100

TIAN Tian, LIU Shuyu, ZHANG Yan, ZHOU Xia, JIAO Hui, LI Xiuqin. Mass Spectrometry Matrix Effect Study for the Trace Analysis of Chloramphenicol Residues in Honey[J]. Metrology Science and Technology, 2021, 65(5): 77-82, 100. doi: 10.12338/j.issn.2096-9015.2020.9037

Citation:

TIAN Tian, LIU Shuyu, ZHANG Yan, ZHOU Xia, JIAO Hui, LI Xiuqin. Mass Spectrometry Matrix Effect Study for the Trace Analysis of Chloramphenicol Residues in Honey[J]. Metrology Science and Technology, 2021, 65(5): 77-82, 100. doi: 10.12338/j.issn.2096-9015.2020.9037

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Mass Spectrometry Matrix Effect Study for the Trace Analysis of Chloramphenicol Residues in Honey

doi: 10.12338/j.issn.2096-9015.2020.9037

TIAN Tian^{1, 2
,},
LIU Shuyu^{2
,
,},
ZHANG Yan¹,
ZHOU Xia¹,
JIAO Hui¹,
LI Xiuqin^{1
,
,}

1.
National Institute of Metrology, Beijing 100029, China
2.
Shanghai University of Engineering Science, Shanghai 201620, China

Available Online: 2021-05-08
Publish Date: 2021-06-24

Abstract

Abstract

Organic isotope dilution mass spectrometry (IDMS) is a potential reference method for the accurate measurement of trace components in complex matrix samples. However, the analytical conditions, isotope dilution reagents, matrix effects (MEs), and other factors can also affect the results. In this paper, jujube and wattle honey were used as the study samples to compare the MEs in the trace measurement of chloramphenicol residues in honey under different extraction methods, so as to investigate the influence of MEs on the results, the compensation and elimination methods of MEs.
- honey,
- chloramphenicol,
- matrix effect,
- isotope dilution mass spectrometry,
- liquid chromatography tandem triple quadrupole mass spectrometry (LC-MS/MS)

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References(28)

References

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