Volume 66 Issue 4
Jun.  2022
Turn off MathJax
Article Contents
YANG Zhijie, ZHOU Qianqian, LIANG Juncheng, FAN Zihao, LI Zeshu, FAN Fuyou, LIU Haoran, TUO Fei, ZHANG Jian, SUN Quanfu. Development of a Metrological Standard Device for Measuring 131I Activity in Human Thyroid[J]. Metrology Science and Technology, 2022, 66(4): 95-100. doi: 10.12338/j.issn.2096-9015.2021.0655
Citation: YANG Zhijie, ZHOU Qianqian, LIANG Juncheng, FAN Zihao, LI Zeshu, FAN Fuyou, LIU Haoran, TUO Fei, ZHANG Jian, SUN Quanfu. Development of a Metrological Standard Device for Measuring 131I Activity in Human Thyroid[J]. Metrology Science and Technology, 2022, 66(4): 95-100. doi: 10.12338/j.issn.2096-9015.2021.0655

Development of a Metrological Standard Device for Measuring 131I Activity in Human Thyroid

doi: 10.12338/j.issn.2096-9015.2021.0655
  • Available Online: 2022-03-12
  • Publish Date: 2022-06-02
  • To solve the problem of direct 131I activity measurement in human thyroid for radiological protection and diagnosis and treatment in nuclear medicine, and the problem of traceability of related instruments for 131I activity measurement in human thyroid, a portable on-site radioactivity measurement metrological standard device was developed. In combination with the IAEA/ANSI neck phantom, the detection efficiency calibration and activity determination methods of the standardization were studied. Through experimental measurement and simulation calculation, the efficiency curve at different detection distances was determined, and the traceability method of 131I activity in the human thyroid was established. The minimum detectable activity reached 4.67 Bq when the standard was directly measured close to the neck for 600s; the portable gamma spectrometer used to measure the activity of 131I in the human thyroid was calibrated with the relative expanded uncertainty of 5.5% (k=2). The development of this standard has established a key equipment foundation for the accurate measurement and traceability of 131I activity in occupational health monitoring, nuclear emergency, and diagnosis and treatment of thyroid diseases.
  • loading
  • [1]
    邢家骝, 朱家瑞, 丁勇. 碘-131治疗甲状腺疾病[M]. 北京: 人民卫生出版社, 2011.
    [2]
    陆永经. 放射性131I在甲状腺功能亢进治疗中的临床应用研究[J]. 中国医药导刊, 2013, 15(4): 703-704. doi: 10.3969/j.issn.1009-0959.2013.04.089
    [3]
    王荣福. 放射性核素131I治疗分化型甲状腺癌的应用与进展[J]. 中华医学信息导报, 2009(9): 19-20.
    [4]
    霍艳雷, 王丹阳, 王辉, 等. 放射性碘标记MIBG在儿童神经母细胞瘤诊治中的应用[J]. 中华核医学与分子影像杂志, 2017, 37(3): 173-176.
    [5]
    邓飞, 周睿东, 蒋岚, 等. 核医学含碘废水排放管理的一些问题[J]. 辐射防护, 2018, 38(3): 79-84.
    [6]
    郭秋菊. 切尔诺贝利核事故时稳定碘的服用及各国对策[J]. 中华放射医学与防护杂志, 2000, 20(2): 143-144. doi: 10.3760/cma.j.issn.0254-5098.2000.02.041
    [7]
    王维良. 对轻水堆事故放射性碘污染的新认识-失水事故中释放的放射性碘-131不是污染环境的主要核素[J]. 国外核新闻, 1981(10): 24.
    [8]
    赵杨军, 顾志杰. 核电厂常规运行工况下放射性惰性气体和碘的释放源项计算[J]. 辐射防护, 2010(4): 34-39.
    [9]
    梁婧, 张庆召, 林志凯, 等. 碘-131治疗过程人员受照剂量分析[J]. 中国职业医学, 2015, 42(3): 318-321.
    [10]
    张志东, 暴晓琳. 放射性核素碘-131的治疗甲状腺癌时医务人员的辐射防护[J]. 医学动物防制, 2007, 23(10): 790-791. doi: 10.3969/j.issn.1003-6245.2007.10.050
    [11]
    McGowan, DR, Pratt, et al. Iodine-131 monitoring in sewage plant outflow[J]. Journal of Radiological Protection, 2014(34): 1-14.
    [12]
    Tokonami S, Hosoda M, Aki Ba S, et al. Thyroid doses for evacuees from the Fukushima nuclear accident[J]. Scientific Reports, 2012, 2: 507-510. doi: 10.1038/srep00507
    [13]
    彭玄, 张建峰, 拓飞, 等. 便携式γ谱仪在放射工作人员甲状腺131I监测中的应用[J]. 中国辐射卫生, 2021, 30(1): 34-37,43.
    [14]
    王红波, 张庆召, 张震, 等. 核医学科工作人员职业性内照射研究进展[J]. 中国辐射卫生, 2016, 25(2): 251-254.
    [15]
    梁珺成. 一种涉及甲状腺内照射碘测量的智能测量系统: CN111568382A [P]. 2020-08-25.
    [16]
    王静. 一种可升降的甲状腺摄碘功能测试仪: CN210871535U [P]. 2020-06-30.
    [17]
    钟华强, 骆志平, 刘森林, 等. 一种便携式应急甲状腺辐射监测仪的研制[J]. 中国辐射卫生, 2019, 28(6): 84-87.
    [18]
    ANSI. Thyroid Phantom Used in Occupational Monitoring: ANSI/HPS N13.44 [S]. US: American National Standards Institute, 2014.
    [19]
    范梓浩, 刘皓然, 梁珺成, 等. γ能谱分析中放射性核素活度的蒙卡修正方法及实验验证[J]. 计量技术, 2020(5): 95-99,114.
    [20]
    L'Annunziata M F. Handbook of Radioactivity Analysis [M]. Elsevier Science & Technology, 2012.
    [21]
    国家质量监督检验检疫总局. 测量不确定度评定与表示: JJF 1059.1-2012 [S]. 北京: 中国标准出版社, 2012.
    [22]
    靳浩元, 刘军. 测量不确定度的评定方法及应用研究[J]. 计量科学与技术, 2021, 65(5): 124-131. doi: 10.12338/j.issn.2096-9015.2020.9002
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(9)  / Tables(5)

    Article Metrics

    Article views (557) PDF downloads(48) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return